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Hereditary Hemorrhagic Telangiectasia (HHT)

HHT is a genetic disorder of the blood vessels, which affects approximately 1 in 5,000 people. It affects males and females from all racial and ethnic groups. The disorder may also be referred to as Osler-Weber-Rendu (OWR) after several doctors who studied HHT about 100 years ago. In 1896 Dr. Rendu first described HHT as a hereditary disorder involving nosebleeds and characteristic red spots that was distinctly different from hemophilia. Before Dr. Rendu's work, doctors did not understand that individuals with what we now call HHT have abnormalities of their blood vessels, not a clotting problem in the blood itself. More than one hundred years later, HHT is still often misdiagnosed in affected individuals and many doctors do not understand all of its manifestations.

Signs and Symptoms

Symptoms of HHT vary greatly, even within a family. The location of telangiectases and /or AVMs in the body determines what problem(s) someone with HHT might have. Most commonly affected organs are the nose, lungs, GI tract, brain, and spine-in that order.

Telangiectases in the nose, along with the nosebleeds they cause, are the most common symptom of HHT. About 95% of people with HHT have recurring nosebleeds by the time they reach middle age. The average age at which nosebleeds begin is 12, but they can begin as early as infancy, or as late as adulthood. Nosebleeds can be as infrequent as a couple per year or can occur daily. When a nosebleed occurs, it can last anywhere from a few seconds, up to several hours in some cases.

For more information on HHT, visit HHT Foundation International.

BleedArrest Nasal Strips are produced from a flexible foam and are designed to accelerate blood clotting—especially in the nose. Click here for more information.

Information on HHT taken from HHT Foundation International.